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The superior in vitro potency and corneal penetration of trifluridine suggest that it should be the first uBy for topical пTable 7-6 ф Characteristic Features of Infectious Bovine Keratoconjunctivitis ппINFECTIOUS BOVINE MALIGNANT CATARRHAL INFECTIOUS BOVINE CLINICAL SIGNS RHINOTRACHEITIS FEVER KERATOCONJUNCTIVITIS пConjunctivitis Systemic signs Keratitis Corneal ulceration Other ocular disease Cause Acute hyperemia Respiratory (Limbal) в None Bovine herpesvirus 1 Acute hyperemia Chemosis Mucosal necrosis Lymphadenopathy (Limbal) в Anterior uveitis Panophthalmitis Blepharitis Alcelaphine herpesvirus 1 Acute hyperemia Blepharospasm FewNone Severe keratitis Moraxella bovis п, topical mitomycin C drops, which have a radiomimetic effect on surrounding cells) may be the cause.
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